{"id":1177,"date":"2017-06-06T08:00:50","date_gmt":"2017-06-06T06:00:50","guid":{"rendered":"https:\/\/xd3kj9bvqee.preview.infomaniak.website\/?p=1177"},"modified":"2017-05-27T16:19:42","modified_gmt":"2017-05-27T14:19:42","slug":"silab-segmentation-derme-matrisome","status":"publish","type":"post","link":"https:\/\/www.industries-cosmetiques.fr\/en\/silab-segmentation-derme-matrisome\/","title":{"rendered":"Silab and the segmentation of the dermis and its matrisome"},"content":{"rendered":"<p>The work of Silab's advanced research department and Dr Florence Ruggiero's* research team on dermal segmentation and its matrisome has been recognized by the international scientific community with the publication of a letter to the editor in the <em>Journal of Investigative Dermatology <\/em>(JID).<\/p>\n<p>A major scientific discovery on the papillary and reticular dermis<\/p><div class=\"indus-dans-articles indus-entity-placement\" style=\"text-align: center;display: flex;justify-content: center;\" id=\"indus-3696830963\"><div class=\"indus-adlabel\">Advertising<\/div><div id=\"indus-4040755514\"><a data-bid=\"1\" data-no-instant=\"1\" href=\"https:\/\/www.industries-cosmetiques.fr\/en\/ad\/24744\" rel=\"noopener nofollow\" class=\"notrack\" target=\"_blank\" aria-label=\"site-industries-cosmetiques Promotional graphic for Siemens&quot; &quot;The Beauty Thread&quot; videocast series, with French text about faster formulation and better control thanks to enterprise recipe management. Launch in April 2026, with a blue &quot;Discover Episode 1&quot; button. Abstract background.\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.industries-cosmetiques.fr\/wp-content\/uploads\/2026\/04\/12296_SIEMENS_Videocast_series_BAN2_1200x1200.jpg\" alt=\"site-industries-cosmetiques Promotional graphic for Siemens&quot; &quot;The Beauty Thread&quot; videocast series, with French text about faster formulation and better control thanks to enterprise recipe management. Launch in April 2026, with a blue &quot;Discover Episode 1&quot; button. Abstract background.\"  srcset=\"https:\/\/www.industries-cosmetiques.fr\/wp-content\/uploads\/2026\/04\/12296_SIEMENS_Videocast_series_BAN2_1200x1200.jpg 1200w, https:\/\/www.industries-cosmetiques.fr\/wp-content\/uploads\/2026\/04\/12296_SIEMENS_Videocast_series_BAN2_1200x1200-300x300.jpg 300w, https:\/\/www.industries-cosmetiques.fr\/wp-content\/uploads\/2026\/04\/12296_SIEMENS_Videocast_series_BAN2_1200x1200-1024x1024.jpg 1024w, https:\/\/www.industries-cosmetiques.fr\/wp-content\/uploads\/2026\/04\/12296_SIEMENS_Videocast_series_BAN2_1200x1200-150x150.jpg 150w, https:\/\/www.industries-cosmetiques.fr\/wp-content\/uploads\/2026\/04\/12296_SIEMENS_Videocast_series_BAN2_1200x1200-768x768.jpg 768w, https:\/\/www.industries-cosmetiques.fr\/wp-content\/uploads\/2026\/04\/12296_SIEMENS_Videocast_series_BAN2_1200x1200-12x12.jpg 12w, https:\/\/www.industries-cosmetiques.fr\/wp-content\/uploads\/2026\/04\/12296_SIEMENS_Videocast_series_BAN2_1200x1200-600x600.jpg 600w, https:\/\/www.industries-cosmetiques.fr\/wp-content\/uploads\/2026\/04\/12296_SIEMENS_Videocast_series_BAN2_1200x1200-696x696.jpg 696w, https:\/\/www.industries-cosmetiques.fr\/wp-content\/uploads\/2026\/04\/12296_SIEMENS_Videocast_series_BAN2_1200x1200-1068x1068.jpg 1068w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" class=\"no-lazyload\" width=\"300\" height=\"300\"   \/><\/a><\/div><\/div>\n<p>The upper dermis, known as the papillary dermis, and the deeper dermis, known as the reticular dermis, are structurally and functionally different. Fibroblasts, the cells responsible for extracellular matrix synthesis, are thought to be at the origin of this segmentation.<br \/>\n<em>\"Segmentation of the dermis is a biological research signature dear to <\/em>Silab<em> \" <\/em>says Brigitte Closs, Executive Vice President, Research and Development, Silab. <em>\"When we started working on this subject in 2007, we naturally approached Dr Florence Ruggiero, CNRS Research Director, and her collaborators, recognized worldwide for their expertise in extracellular matrix biology.\"<br \/>\n<\/em>Dr Florence Ruggiero's research team and the Silab advanced research department have demonstrated for the first time the signature of a specific gene expression in papillary and reticular fibroblasts in relation to the matrisome, defined as the set of genes coding for extracellular matrix proteins and its associated proteins.<br \/>\n<em>\"This letter to the editor in one of the most prestigious scientific dermatology journals is indisputable recognition of the quality of the research work carried out by the two teams. It reinforces our expertise in this field and opens up new prospects for the development of innovative, high-performance natural cosmetic solutions, particularly in the fight against skin ageing. It could also have <\/em><em>bioengineering repercussions of skin substitutes to make them ever closer to the physiological reality of the skin.\" <\/em>concludes Brigitte Closs.<\/p>\n<p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>Les travaux du d\u00e9partement de recherche avanc\u00e9e Silab et de l\u2019\u00e9quipe de recherche du Dr Florence Ruggiero* sur la segmentation du derme et son matrisome sont reconnus par la communaut\u00e9 scientifique internationale avec la publication d\u2019une lettre \u00e0 l\u2019\u00e9diteur dans le Journal of Investigative Dermatology (JID). Une d\u00e9couverte scientifique majeure sur le derme papillaire et [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":1178,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"external_url":"","footnotes":""},"categories":[51],"tags":[60],"class_list":{"0":"post-1177","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-ingredients","8":"tag-info-produit"},"acf":{"nc":null,"nc2":null,"nc3":null,"nc4":null,"nc5":null},"_links":{"self":[{"href":"https:\/\/www.industries-cosmetiques.fr\/en\/wp-json\/wp\/v2\/posts\/1177","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.industries-cosmetiques.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.industries-cosmetiques.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.industries-cosmetiques.fr\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.industries-cosmetiques.fr\/en\/wp-json\/wp\/v2\/comments?post=1177"}],"version-history":[{"count":0,"href":"https:\/\/www.industries-cosmetiques.fr\/en\/wp-json\/wp\/v2\/posts\/1177\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.industries-cosmetiques.fr\/en\/wp-json\/wp\/v2\/media\/1178"}],"wp:attachment":[{"href":"https:\/\/www.industries-cosmetiques.fr\/en\/wp-json\/wp\/v2\/media?parent=1177"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.industries-cosmetiques.fr\/en\/wp-json\/wp\/v2\/categories?post=1177"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.industries-cosmetiques.fr\/en\/wp-json\/wp\/v2\/tags?post=1177"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}