BioTech4 AntiGray: postbiotic biotechnology to reverse graying hair

Chemyunion introduces BioTech4 AntiGray, a post-biotic active ingredient that restores natural melanin production and combats graying hair.

The search for effective solutions to the visible signs of hair ageing takes another step forward. While much of the global hair care market still focuses on camouflaging gray hair with synthetic pigments, Chemyunion introduces an innovative biotechnology-based approach: BioTech4 AntiGray (INCI: Lactobacillus Ferment Lysate). Developed from a proprietary platform, this post-biotic ingredient acts directly on the biological mechanisms responsible for hair graying. Rather than simply hiding grey strands, it aims to stimulate the natural resumption of melanin production within the hair follicle, gradually restoring the functionality of the hair pigmentation system.

Scientific evidence and proven results

The appearance of gray hair is one of the most obvious signs of hair aging, generally associated with the progressive decline in melanocyte activity in the hair bulb, often exacerbated by oxidative stress. This process alters the synthesis and transfer of melanin to the hair fiber, leading to a progressive loss of natural hair color. In this context, BioTech4 AntiGray acts as a biological signaling agent, promoting an integrated approach that includes:

- Stimulation of melanogenesis: reactivates melanocyte activity in the hair follicle, supporting the resumption of melanin production. - Pigment cell support: helps maintain melanocyte stem cells and the functionality of the hair pigmentation system. - Protection against oxidative stress: stimulates the expression of antioxidant genes to preserve the integrity of melanocyte cells. - Compliance with clean beauty trends: with a natural origin content of 98.7 %, it aligns with the growing demand for sustainable, biotechnology-based solutions.

The results of BioTech4 AntiGray have been demonstrated through ex vivo and in vivo studies, confirming its potential application in hair formulations targeting the prevention and reversal of hair graying. In an ex vivo model using human hair follicles from a 50-year-old male donor, a 43 % increase in melanin content in the hair bulb was observed, confirming the ingredient's ability to stimulate pigment activity directly at root level.

Potential for innovative formulations

In addition, an in vivo study conducted with 90 volunteers (men and women aged between 20 and 55) over a 120-day period, using a formulation containing 3 % of active ingredient, obtained significant results:

- 76.7 % of participants reported a visible reduction in gray hair. - 27 % increase in hair color uniformity. - Noticeable reduction in the intensity of white/gray strands. - 90 % overall satisfaction after using formulations containing BioTech4 AntiGray.

These results indicate that modulation of biological pigmentation mechanisms can contribute to the gradual recovery of natural hair color. Thanks to its highly technical nature, BioTech4 AntiGray can be integrated into a wide range of hair care products, including toners and treatment shampoos, enabling the development of advanced solutions focused on hair longevity and the preservation of natural hair color. By acting directly at the biological origin of the graying process, this ingredient paves the way for a new generation of hair care products that go beyond camouflage, offering functional care for the hair pigmentation system.

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