EleVastin is a targeted solution to gravity-induced skin sagging. According to Gattefossé, the ingredient boosts skin elasticity and provides the support it needs to cope with this downward pressure.
Renewal of the skin's elastic potential
Gattefossé reports that EleVastin's efficacy has been demonstrated in models of increasing complexity. The active ingredient increases the synthesis of key proteins involved in the production and maintenance of functional elastic fibers: elastin, fibrillin-1 and fibulin-5. It also protects elastic fibers against degradation by elastases. Through this mechanism of action, it ensures an increase in elastic fiber density coupled with improved skin elasticity. This last result was obtained on an advanced spheroid model developed entirely in our cell culture laboratory.
Combating the signs of gravity-induced ageing
Tested at only 1 % and on 37 volunteers, the active ingredient demonstrated its ability to reduce sagging in the lower part of the face. Skin elasticity is significantly improved vs. placebo. Facial contours are better defined, and deep, vertical wrinkles are significantly reduced. An original measurement of the effects of gravity on facial morphology was carried out, confirming EleVastin's ability to limit the impact of gravity on the signs of aging.
A 100 % ingredient of natural origin
Traditional plants used for therapeutic or culinary purposes are an unlimited source of inspiration for Gattefossé scientists. One such plant, Murraya koenigii, has been used for hundreds of years in Ayurvedic medicine and cooking. In association with its long-standing local partner, the leafy stems of the Murraya koenigii tree are harvested by hand in the preserved environment of Reunion Island, on plots managed without inputs (no fertilizers or pesticides). Traceability is guaranteed from the tree to the Gattefossé laboratories. A synergy of phytomolecules is obtained thanks to an innovative blend of plant-derived solvents and a rational extraction process. The active ingredient is Cosmos approved and has a natural origin content of 100 % according to ISO 16128.
"The phytochemical content of Murraya koenigii is both very rich and well described, enabling us to adopt a very methodical plant extraction research strategy. By adjusting solvent polarity, we were able to target more specifically certain molecular families such as flavonoids, phenolic acids and alkaloids. At the same time, in our laboratories and in partnership with experts in proteomics and biomechanics, we have developed innovative in vitro evaluation models. These have enabled us to provide a comprehensive demonstration of the ingredient's biological efficacy".explains Boris Vogelgesang, Cosmetic Active Ingredients R&D Director.
"EleVastin is the fruit of Gattefossé's latest advances in plant extraction and objectification. In our cell culture laboratory, our scientists develop in vitro models that are ever closer to real skin conditions. The reproducibility of results obtained with EleVastin on different models is a real guarantee of the ingredient's efficacy. What's more, EleVastin's excellent naturalness profile is the result of several years' work on developing solvents and finding the perfect match with plant material. We are very proud to supply the cosmetics market with this robust and 100 % natural active ingredient".reports Laurie Canel, Cosmetic Active Ingredients Product Manager.
