Osmolya: a new bio-inspired active ingredient from Expanscience

Expanscience unveils Osmolya, a naturally-derived active ingredient optimizing cellular hydration, at In-Cosmetics Global 2026.

At In-Cosmetics Global 2026, Laboratoires Expanscience are presenting Osmolya, a new bio-inspired active ingredient designed to boost skin and hair hydration. This extract, found in Iresine weberbaueri, a plant endemic to Peru, is designed to improve cellular osmoregulation.

A bio-inspired active ingredient to meet modern hydration challenges

Osmolya is a water-soluble extract rich in betaine (≥13%) and polyphenols (≥6%), key molecules in the protection against osmotic, oxidative and inflammatory stress. Like Iresine w. Osmolya :

  • activates cellular response to osmotic stress
  • increases expression and production of osmolyte transporters (TAUT, SMIT and BGT1)
  • improves the skin barrier, by stimulating its key markers (HAS3, TGAS1, involucrin) and increasing the expression of occludin
  • reduces osmotic stress-induced cell damage, significantly reducing inflammation and oxidative stress

This triple action positions Osmolya as an active ingredient capable of meeting the growing need for cellular hydration.

Proven effectiveness on the skin

Clinical studies carried out on a multi-ethnic panel reveal that Osmolya at 2% improves skin hydration from the very first hour, with lasting results over time. These results were confirmed by corneometry evaluations and PIE analysis on the face. Evaluations also show a reduction in dryness, desquamation and roughness.

Analyses also show a significant improvement in the thickness of the stratum corneum, measured by Raman spectroscopy, confirming its role in strengthening the skin barrier. Volunteers reported an increased perception of hydration as early as 3 days, confirmed after 28 days of use.

Proven effectiveness on hair, too

Osmolya also acts on the hair fiber thanks to its richness in osmolytes and polyphenols:

  • moisturizes hair from within, increasing the fraction of water strongly bound to the hair fiber
  • strengthens hair fiber
  • significantly reduces frizz and improves curl definition on type 3A strands

Compliant with Cosmos and Natrue standards, Osmolya meets international standards for naturalness, quality and transparency, guaranteeing that the ingredient is derived from natural raw materials and transformed using environmentally-friendly processes.

An innovation perfectly aligned with Expanscience's CSR vision

Armelle Le Peniec, Director of Cosmetic and Nutraceutical Assets at Laboratoires Expanscience, says: « Thanks to its bio-inspired nature and multi-benefit efficacy, Osmolya embodies Laboratoires Expanscience's ambition to develop eco-designed active ingredients for well-being that are increasingly inspired by nature and the living world. "

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