In 2007, SILAB developed Whitonyl by focusing on the major player in melanogenesis, the melanocyte, through the study of tyrosinase activity, melanosome transport and SCF (Stem Cell Factor) signaling. Thanks to innovative approaches, SILAB is now able to provide additional efficacy data by exploring the impact of the environment on melanogenesis and Whitonyl's ability to regulate two novel pathways:
- melanocyte epigenome;
- communication via keratinocyte exosomes
The development of new expertise dedicated to exosomes has enabled SILAB to be one of the first to identify this mode of intercellular communication and its effects on photo-induced pigmentation.
By modulating the various mechanisms that regulate melanogenesis, Whitonyl effectively combats the signs of cutaneous photoaging.
Depigmenting and lightening action
Whitonyl's depigmenting and lightening power has been demonstrated on both Caucasian and Asian skins.
After 56 days of twice-daily application and compared to placebo, Whitonyl at 4% attenuates age spots by :
- significantly increasing the parameters L* (skin clarity) and ITA° (degree of pigmentation);
- reducing the b* parameter (melanin yellow pigmentation).
Skin is even and clear, complexion brightens and pigmentation spots fade.
Low environmental impact sourcing
Whitonyl is a natural active ingredient, rich in xylans and galactans, derived from the red seaweed Palmaria palmata (INCI name: Water & Palmaria palmata Extract).
The supply of this marine species is guaranteed to have a low environmental impact, thanks on the one hand to its geographical proximity (mainly to the Atlantic, Channel and North Sea coasts) and on the other hand to its adaptability (fixed to rocks thanks to a disc that facilitates its renewal after harvesting).
Obtained through a non-denaturing manufacturing process, Whitonyl is a patented active ingredient, available in aqueous solution (recommended dose: 1 to 4%) and preservative-free powder form (recommended dose: 0.1 to 1%), in compliance with international cosmetics regulations (Europe, USA, Japan, China).
