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Autophagy, a biological signature Silab in cosmetics

On Monday October 3, Japanese biologist Yoshinori Ohsumi was awarded the 2016 Nobel Prize in Physiology or Medicine for elucidating the biological mechanism of autophagy, a powerful process for degrading and recycling cell constituents. His research has highlighted autophagy's role in a number of pathologies and in aging.

As early as 2006, when autophagy was just background noise in dermatology, Silab's advanced research and university partnerships were deploying a research strategy to understand this machinery and its functions in the skin.

Silab and autophagy: key figures :

  • 10 years of research,
  • 4 national and international patents,
  • 2 theses and 2 partnerships with public research laboratories*,
  • 7 international communications, including 4 publications and 3 conferences,
  • 1 innovation award,
  • 1 international seminar organized by Silab on April 15, 2013 at the Maison de la Chimie, Paris.

Silab is a pioneer and innovator with unique expertise in cutaneous autophagy, based on groundbreaking biological models. This essential modeling approach is a major asset in the exploration of autophagic mechanics. As early as 2009, Silab proposed the active ingredient Celldetox, an autophagy modulator which is available and widely acclaimed on the market today. Acting on autophagy markers (lysosomes, LC3), this biotechnological active ingredient revives the radiance of intoxicated skin and smoothes microrelief after 14 days; it evens skin tone and erases wrinkles after 28 days. A genuine detoxification and cellular longevity booster, it offers new youthfulness to tired skin. In line with its strategy, Silab continues to extend its research scope to explore new autophagic pathways such as mitophagy and mitochondrial autophagy.

* EA 3842, Homéostasie Cellulaire et Pathologies, Faculté de Médecine, Limoges, France UMR 5239, Molecular Biology of the Cell Laboratory, Ecole Normale Supérieure de Lyon, CNRS - UCBL - ENS Lyon, France.

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