Seppic launches Sepibright, a nutraceutical active ingredient derived from strawberry leaves. Backed by a clinical study, this eco-designed ingredient is presented for cognition and ageing well.

Sepibright marks the arrival of Seppic's first nootropic ingredient. It demonstrates benefits for long-term memory and learning, as well as stress reduction. As the world's population ages, cognitive decline has become a major health concern. This natural process, which can begin as early as the thirties, often translates into a progressive slowdown in memory and information processing speed. Preserving cognitive capacity through proactive nutrition is now a priority for some consumers, and the market for such solutions is booming.

Estimated at around $11 billion in 2024, the global market for supplements dedicated to brain health is expected to reach $23 billion by 2030, posting a robust CAGR of 13 %. In 2024, the memory enhancement segment dominated the market, accounting for almost 25 % of market share.

A premium nutraceutical ingredient derived from strawberry leaves

In response to this need, Seppic has designed Sepibright, a premium nutraceutical active ingredient derived from strawberry leaves. Backed by a clinical study, this eco-designed ingredient draws its efficacy from its standardized composition of polyphenols and ellagitannins. These compounds play an important role in improving cognitive performance, thanks to their antioxidant, anti-inflammatory and neuroprotective properties.

Randomized, double-blind, placebo-controlled clinical trial

A randomized, double-blind, placebo-controlled clinical trial was carried out to demonstrate the efficacy of Sepibright in 98 healthy senior men and women aged 60 to 80 with cognitive difficulties. For 12 weeks, participants received either a daily dose of 300 mg Sepibright or a placebo.

Visual episodic memory: a significant improvement was observed as early as 6 weeks, marked by an 18 % reduction in errors and an 11 % increase in memory score.

Verbal episodic memory: in 60-69 year-olds, Sepibright significantly improved verbal memory after 12 weeks, with a 25 % increase in the number of words recalled (memorization) and a 5.5 % increase in immediate recognition ability.

Perceived stress: Sepibright significantly reduced perceived stress levels in just 6 weeks, a key factor in protecting cognitive performance.

A circular economy approach

Anchored in a circular economy approach, Sepibright is 100 % French in origin, and comes mainly from Plougastel, a commune in Brittany renowned worldwide for the quality of its strawberries. Thanks to a five-year collaboration with local farmers, Seppic transforms traditionally unused strawberry leaves into a high value-added active ingredient, via a solvent-free extraction process inspired by the traditional uses of strawberry leaves in infusions.

For Salma Zahidi, Nutrition Product Manager: « With the launch of Sepibright, Seppic has positioned itself in the brain health market. This ingredient bridges the gap between clinical rigor and responsible commitment, meeting the expectations of consumers who want to take care of their cognitive abilities. "

BASF presents at in-cosmetics Global two revolutionary new cosmetic actives, NeoHelix Regenerate and SkinNexus Collag3n.

BASF announced the launch of two new cosmetic actives, NeoHelix Regenerate and SkinNexus Collag3n, at in-cosmetics Global in Paris. These innovations reflect an integrated approach to skin rejuvenation. NeoHelix Regenerate is a precision peptide that enhances the skin's natural repair mechanisms for adaptive collagen renewal. At the same time, SkinNexus Collag3n redefines the concept of collagen banking by introducing a bio-identical collagen III fragment.

NeoHelix Regenerate: an intelligent peptide for skin regeneration

NeoHelix Regenerate represents a significant advance in the field of targeted skin rejuvenation. This peptide is designed not only to support collagen, but also to reinforce the skin's communication and self-repair mechanisms, which are essential in the face of the effects of time and daily stress. In fact, it is particularly active in damaged areas of the skin.

An in vivo study measured the efficacy of NeoHelix Regenerate on biopsies from five women aged 60-70, demonstrating a 41 % reduction in damaged collagen after 56 days of application. In addition, levels of hyaluronic acid in the body increased by 65 % over the same period. Results also indicated visible improvements in skin thickness, tone and forehead wrinkles, outperforming a competing peptide benchmark.

SkinNexus Collag3n: a new approach to collagen banking

With SkinNexus Collag3n, BASF introduces a recombinant collagen III fragment, responding to growing consumer interest in proactive collagen banking solutions. This ingredient is obtained using a biotechnological yeast fermentation process, and is distinguished from traditional products by its 100 % sequence, identical to that of human collagen.

In a 3D dermis model, SkinNexus Collag3n promoted an environment conducive to collagen balance, showing respective increases of +48 % collagen I, +82 % collagen III and +71 % collagen V. In clinical studies with women aged 53 to 70, topical application measured improvements in skin tone and a visible reduction in wrinkles after four weeks, outperforming a market collagen benchmark used at ten times the concentration.

The Group Berkem enriches its H2Olixir range with H2Olixir Red Vine, a plant water made from organic red vine leaves.

The Berkem Group has developed H2Olixir Red Vine, a plant water made from organic red vine leaves. Produced on its own industrial site, this water was developed by the group's R&D department, drawing on its expertise in plant extraction.

Certification and properties of H2Olixir Red Vine

This water is Cosmos-certified, with 99.3 % of organic and 99.5 % of natural origin. It is recognized for its antioxidant, soothing and refreshing properties, helping to protect the skin from free radicals, improving skin comfort and providing a pleasant sensation of freshness.

H2Olixir Red Vine can be used in a variety of cosmetic applications, including body care for a toning effect, leg and foot care for a refreshing action, and facial care for sensitive skin. This water is part of an upcycling approach, valorizing plant co-products, and can replace up to 100 % of osmosis water in formulas.