New publication with Cerebiome^® for the intestine-brain-skin axis

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12 March 2025

New publication! Lallemand Health Solutions' innovative formula shows significant benefits for occasional stress, sleep quality and skin appearance.

Lallemand Health Solutions is proud to announce the latest results of a proof-of-concept study on Cerebiome^®an innovative psychobiotic developed by Institut Rosell^® for the microbiome and probiotics. This innovative formula has shown significant benefits for occasional stress, sleep quality and skin appearance.

Cosmebiome: Innovative clinical study

The recently published dermatologist-supervised open-label clinical study investigated the effects of Cerebiome® on 35 healthy Caucasian women, aged 30-45, over an 8-week period. Participants took 3 billion CFU of Cerebiome^® once a day.

Significant reduction in perceived stress

The primary outcome measured perceived stress using the PSS-10 scale at the 28^e and 56^e days. The study revealed a significant reduction in perceived stress, with a decrease of 18 % after 4 weeks and 31 % after 8 weeks. In addition, 79 % of participants reported significant improvements in their mental well-being.

image2 JXqWQ- Sponsored content - Product info — Figure 1: Perceived stress score evaluation

Sleep benefits

Secondary results of the study revealed significant improvements in sleep quality. Participants saw a marked improvement in their ability to fall asleep and stay asleep, as well as a reduction in difficulties staying awake during the day.

Benefits for skin appearance

In terms of skin appearance, Cerebiome^® contributed to skin hydration and firmness, reducing the appearance of wrinkles, fine lines and skin tone. A significant increase in skin hydration was noted, with an improvement of 21 % on the face after 8 weeks and up to 18 % on the body. In addition, 85 % of women reported feeling that their skin was more hydrated. The study also showed significant improvements in skin tone, firmness and elasticity, with a 12 % increase in skin firmness after 8 weeks of taking Cerebiome.^®. The Cosmebiome study also showed significant improvements in reducing the appearance of fine lines and wrinkles. After just 4 weeks of taking Cerebiome^®In the face, participants saw a 7 % reduction in the appearance of facial wrinkles, rising to 17 % after 8 weeks. The forehead area showed even more pronounced results, with a reduction of 12 % after 4 weeks and 21 % after 8 weeks. What's more, 82 % of women reported that their skin was smoother and had an improved texture, demonstrating the powerful impact of Cerebiome^® on improving the appearance, texture and overall complexion of the skin.

site-industries-cosmetiques Bar chart illustrating skin improvements on days 28 and 56 compared with baseline. For body elasticity: 6 % at 4 weeks, 11 % at 8 weeks. Cerebiome-enhanced facial radiance shows: 8 % at 4 weeks, 13 % at 8 weeks. Uniformity reaches: 9 % at 4 weeks, culminating in skin perfection with. — Figure 2: % skin change at days 28 and 56 relative to baseline

These results underscore the overall benefits of Cerebiome^® for holistic mental well-being and healthy skin

Elodie Aragon, Product Manager at Lallemand Health Solutions, details the potential impact of the study on the nutricosmetics market: " Cerebiome^® is already a well-known and easy-to-formulate psychobiotic on the dietary supplement market, with numerous commercial successes worldwide. With this innovative and unique study, we offer our customers the possibility of solutions for the booming nutricosmetics market. This new study enables our customers to make beauty claims with this combination of two probiotic strains".

Applications

The formula is available in a variety of galenic forms, including soluble powders, orodispersible powders, capsules, sachets and more. It can be formulated with ingredients such as riboflavin (vitamin B2) and folic acid (vitamin B9) for skin stress and anti-aging, vitamin B6 for stress/mood and skin balance, melatonin and vitamin B6 for sleep and skin balance, and vitamin C and copper for energy and radiant skin. Cerebiome^® and other documented strains can support beauty claims in Europe. From lab to counter, Lallemand Health Solutions has the control and expertise to produce top-quality, tailor-made probiotic formulations in state-of-the-art facilities certified to the highest quality.

Meet the team at in-cosmetics global (stand 1D141) in Amsterdam, Netherlands, April 8-10 to discuss this innovative formula and how you can bring it to your market.

* The formulas claimed are based on scientific data from strains and comply with local regulations.

3. Kassem, O., Tremblay, A., Ghaly, M. S. W., Oula, M.-L., Bronner, S. and Binda, S. (2025). Subjective evaluation of the effects of a probiotic formulation on skin quality in young adult women: Open-label proof-of-concept study. International Journal of Probiotics and Prebiotics, 20(1), 1-9. https://doi.org/10.37290/ijpp2641-7197.20:1-9

Elodie Aragon, Product Manager
Lallemand Health Solutions
[email protected]
lallemand-health-solutions.com/en/

About Cerebiome - A game-changing psychobiotic

Cerebiome^® combines two unique strains with complementary effects: Lactobacillus helveticus Rosell^®-52 and Bifidobacterium longum Rosell^®-175, at a concentration of 3 billion CFU per day, and offering particularly good shelf stability, even at room temperature. A pioneering psychobiotic developed by Institut Rosell^® for the Lallemand microbiome and probiotics, which has been involved in research into the mental health applications of probiotics since 1929. It has been extensively researched, including 10 clinical studies on stress and mental well-being, and more than 10 preclinical studies revealing 8 distinct modes of action on the microbiome-gut-brain axis. Notably, Cerebiome® is the only psychobiotic whose health claims have been validated in Canada and Brazil, demonstrating positive impacts on mood, stress and stress-related intestinal discomfort.

About Lallemand Health Solutions

With 90 years of expertise, Lallemand Health Solutions is a world leader in the probiotics industry, specializing in the development, production and marketing of bacterial and yeast-based probiotic supplements for human health.

Traceability and authentication: Selinko joins Japanese group Toppan

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The editorial staff

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12 March 2025

Toppan, a Japanese specialist in printing and authentication solutions, has acquired Selinko, a European pioneer in NFC authentication solutions for luxury and spirits brands.

Founded in 2012 in Belgium, Selinko has become a major European player in digital authentication, with a unique NFC technology already adopted by over 45 brands in the luxury, spirits and lifestyle sectors. The company has developed advanced expertise in creating personalized solutions that transform authentication into an immersive customer experience.

With over 120 years of expertise in secure printing, the Toppan Group has developed in-depth knowledge in the design and development of NFC and RFID tags specifically adapted to a wide range of products, containers and packaging.

A comprehensive offer

Selinko's integration into the Toppan group will combine Toppan's advanced NFC tag and RFID chip technologies with Selinko's authentication platform. This will enable us to offer :

Tamper-proof authentication to combat market detour and counterfeiting,
Full product traceability, from production to sale and recycling, in compliance with local regulations such as the future Digital Product Passport, the European RGPD and the China Data Protection Act;
Enhanced customer relations for luxury brands thanks to personalized, interactive services and content;
Innovative sustainability solutions, extending the life of products with long-term warranties and securing the second-hand market with digital property certificates.

Digital authentication and traceability solutions for IoT (Internet of Things) and intelligent packaging for the European and Asian luxury goods industry can be operated anywhere in the world, including China.

Dealing with counterfeiting

Growing consumer demand for transparency, legislation and the rise in counterfeiting are putting considerable pressure on the sector. Counterfeiting cost 4 billion euros¹ to luxury brands and 1.3 billion euros to European wine and spirits companies, resulting in the loss of more than 20,000 jobs, particularly in Spain, France, Italy, Germany and the United Kingdom.².

"With Selinko, brands can better control and optimize their entire supply chain, from the start of production to after-sales. Our authentication solution protects the unique expertise of luxury brands by guaranteeing the authenticity of each piece and preserving the value and excellence of their creations. It effectively defends them against counterfeiting. Our solution also enables them to showcase their history and expertise by sharing their creative process with their customers. They can thus highlight their artisanal techniques and communicate directly on the uniqueness of each product", says André Ghighi, Selinko Sales Director.

Patrick Eischen, Selinko's founder, will continue to steer the company's product vision and expertise. The current team remains in place and is being strengthened, notably with the recent opening of an office in Paris and the expansion of the team.

"This acquisition represents a major step forward in our digitalization strategy. Selinko's expertise in authentication technologies, combined with our long-standing know-how in design and integration and our global manufacturing capabilities in RFID product development, enables us to offer a unique global solution to meet the authenticity and traceability challenges of luxury and spirits brands."says Hiroki Shibatani, Director and Executive Vice President of Toppan Digital, the Toppan Holdings company that manages digital transformation solutions for the entire group.

¹^{https://www.eslsca.fr/blog/contrefacon-un-secteur-qui-la-cote}

²^{https://www.larvf.com/,la-contrefacon-d-alcool-une-perte-seche-pour-l-economie-europeenne,4508014.asp}

A new durable crystalline resin

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The editorial staff

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11 March 2025

Axilone, a specialist in plastic injection and aluminum processing for luxury cosmetics, and Eastman, a materials producer, have developed a recycled and recyclable crystalline resin with a glass-like brilliance.

Sustainability is at the heart of the strategy of Axilone and Eastman, long-standing partners. The two companies have revealed the fruit of a new collaboration: an innovative solution aimed at offering sustainable packaging options while preserving high-end aesthetics and personalization.

They have developed a recycled and recyclable crystalline resin with glass-like brilliance for premium applications. This new addition to the Cristal One resin range. Cristal One Renew IM812 is designed to offer copolyester-like performance in a recyclable material (RIC1). Cristal One IM812 and Cristal One Renew IM812 have received RecyClass recyclability certification and are classified as fully compatible with Europe's existing recycling processes for PET bottles.

This resin offers several advantages for beauty brands: it is recyclable and made up of up to 100 % of certified* recycled content, with no compromise on color or performance. It combines the properties of a durable material with the ability to produce thick-walled parts with very high levels of transparency and gloss.

Thanks to Axilone's expertise in injection molding, it enables us to develop multiple applications for all segments of the sector: filling solutions for skincare and perfumery, and packaging for make-up and skincare (lipsticks, sun sticks, etc.).

"Eastman is proud of this project, which reflects the power of collaboration and shared expertise to define the future of cosmetic packaging, enabling recycled and recyclable materials to embody the codes of luxury beauty, says Tara Cary, Global Marketing Manager Cosmetics at Eastman. Cristal One Renew IM812 not only meets the high standards of aesthetics, touch and feel required by leading brands, but also supports their commitments to sustainable development."

"In our opinion, this new resin is very promising, as it meets several criteria to which we are particularly attached and for which we are a force to be reckoned with on behalf of our customers: recyclability - with the choice of materials that fit into established recycling channels, the possibility of single-material designs of varying thicknesses, and the integration of certified recycled materials, without compromising on aesthetics and high-end perception."explains Reynald Trochel, Director of Innovation at Axilone.

_{* Recycled content allocated by mass balance}

Skincare: a growing market

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11 March 2025

site-industries-cosmetiques A glass jar containing a peach-colored cream rests on a glossy black surface, embodying the essence of luxury skincare. Two pink flowers with large petals are cleverly arranged next to it. The lighting of the scene beautifully highlights the texture of the cream and the delicate flowers.

Cosmetic Skin Care - Global Strategic Business Report" report has been added to ResearchAndMarkets.com's offering.

The global skincare market was valued at 146.6 Bn$ in 2024 and is expected to reach 197.2 Bn$ by 2030, according to the Irish research firm, with growth of 5.1% from 2024 to 2030.

The growth of the cosmetic skin care market is driven by several factors. Rising disposable incomes and the growth of the global middle class have broadened the consumer base ready to invest in high-end skin care products. The pervasive influence of social media and beauty influencers has amplified consumer awareness and interest in skincare, driving demand for the latest products and trends. Aging populations, particularly in developed countries, are looking for effective anti-aging solutions, driving demand for products targeting wrinkles, fine lines and age spots.

In addition, the rising prevalence of skin conditions due to pollution, stress and lifestyle factors has increased the need for specialized skin care treatments. Innovations in product formulation, packaging and marketing strategies, as well as the expansion of e-commerce platforms, have further stimulated market growth. These factors, combined with ongoing advances in dermatological science and consumer preferences for personalized, effective skincare solutions, are ensuring that the cosmetic skincare market continues to expand.

The ResearchAndMarkets report points out that ". Technological advances and scientific research have had a profound impact on the cosmetics industry, leading to the development of innovative and more effective products. The integration of biotechnology and dermatological research has enabled the creation of personalized skincare solutions tailored to the skin's individual needs. Breakthroughs in ingredient delivery systems, such as nanotechnology, have improved the efficacy of active ingredients, ensuring deeper penetration and better results. In addition, the rise of clean beauty and the demand for natural and organic products have driven brands to formulate skincare lines free from harmful chemicals, with an emphasis on safety and sustainability."

_{Photo: Aesthetic Journey / Pixabay}

To put an end to dandruff

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10 March 2025

Givaudan Active Beauty presents DandErase, a botanical active designed to eradicate dandruff and restore scalp health. This molecule is produced by green fractionation from the petals of Crocus sativus L. (saffron), sustainably sourced in Morocco.

Dandruff is a widespread scalp condition. Malassezia overgrowth is a key factor in this condition, which results in oily yellow flakes, itching and, often, inflammation.

Malassezia yeast is naturally present in the skin's microbiota, but environmental factors can upset the initial balance and trigger the appearance of dandruff.

Botanical active ingredient 100 % of natural origin, DandErase tackles both the root causes and symptoms of dandruff thanks to a complete mode of action:

Malassezia growth inhibition
Reduced inflammation and erythema
Reduces itching and scalp discomfort
Restores the barrier function of the skin and scalp
Action to balance the microbiome for long-lasting anti-dandruff effects.

According to Givaudan Active Beauty, clinical trials show a positive result with 95 % of dandruff reduction in three days for all participants. By rebalancing the scalp microbiome, it effectively soothes itching and inflammation while preventing rebound effects. Its benefits last beyond the treatment period, with dandruff continuing to diminish even two weeks after discontinuation. This long-lasting efficacy is attributed to its ability to stabilize the scalp interabiome and selectively target Malassezia.

Givaudan Active Beauty will present this new ingredient and its marketing concept S3D Terralogy at in-cosmetics Global, to be held in Amsterdam, the Netherlands, from April 8 to 10, 2025.

Expanscience supports the Joséphine association

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7 March 2025

To mark International Women's Rights Day, Expanscience, through its Actifs Cosmétiques business, is announcing its support for the Joséphine association to help women in precarious situations.

A B Corp-certified company with a mission since 2021, Laboratoires Expanscience has been enhancing the value of the plant world by developing innovative natural cosmetic active ingredients since 1977. The company has decided to support the Joséphine association, France's leading network of solidarity-based beauty salons: 1 % of sales of its Pixalia active ingredient, a cosmetic ingredient designed for skin and hair care, will be donated by the company to the association each year.

For several years now, associations have been observing a worrying increase in the proportion of women in highly precarious situations. These situations have an impact on their health, and affect the self-confidence and self-esteem they need to achieve their personal and professional goals. Founded in 2006, the Joséphine association offers wellness treatments to women in precarious situations, to help them reintegrate into society and the workplace and regain control of their lives.

This first meaningful partnership for Expanscience's Actifs Cosmétiques business - which strives to promote global well-being for each individual - will help to support women in fragile situations, in order to help them achieve their full potential. empowerment.

Since the association was founded, over 11,000 women have been welcomed into the Josephine salons, contributing to their reintegration and emancipation.

"We are committed to making this partnership with the Joséphine association a long-term one, in order to provide long-term support to women in precarious situations, helping them to improve their self-confidence and self-esteem. This reflects our commitment to developing cosmetic active ingredients with a holistic approach, aiming to improve the well-being of body and mind."stresses Angéline Rocherieux, Cosmetic Active Ingredients Marketing Manager at Laboratoires Expanscience.

Nadège Moniez, Development Manager, Josephine Association: "At Joséphine, we believe that access to wellness care is a powerful lever for women's empowerment."

_Photo:_{Social Butterfly}_{/ Pixabay}

A biomimetic ceramide to preserve the scalp barrier

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The editorial staff

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7 March 2025

Croda Beauty Actives has unveiled Sphingo'HAIR Drypure, a unique long-chain fatty acid derived from bio-fermentation, ceramide NP, acting as a cement in the barrier structures of the scalp and hair.

Studies have shown that this active ingredient has a significant impact on scalp health by strengthening the skin's barrier function. It also increases scalp hydration, reduces desquamation and soothes inflammation. It also helps maintain the moisture balance of the hair fiber. It also smoothes hair cuticles and enhances shine and manageability.

"Preserving our body's natural complex defense mechanisms is the key to longevity.Croda reminds us. One of the first lines of defense is the physical, microbial and chemical barrier. This is particularly true for our skin and hair, which are highly exposed to external aggressors. Hair and scalp have similar barrier structures and form a highly interdependent ecosystem. Ensuring strong, healthy barriers is the basis for scalp well-being and hair protection."

Sphingo'HAIR Drypure contains 100 % natural origin according to ISO16128, is Cosmos approved and IECIC compliant.

_{Photo : StockSnap / Pixabay}

Laboratoire Pyc to present its nutricosmetics innovations at Cosmoprof Bologna

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The editorial staff

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6 March 2025

Aix-en-Provence-based Laboratoire Pyc draws inspiration from nature to develop dietary supplements. At Cosmoprof Bologna (March 20-22, 2025), the company will unveil two new nutricosmetics formulas available under white label. These are Revolistic Collagen, the first orodispersible collagen, and Hair Bloom Ceramides, a totally plant-based hair food supplement formula.

An orodispersible collagen

The first orodispersible collagen powder with a high concentration of di- and tripeptides, Revolistic Collagen is distinguished by its formulation. Its ultra-fine powder dissolves directly in the mouth for rapid absorption and optimal bioavailability. The collagen in Revolistic Collagen has a very low molecular weight (500 Dalton) and contains four times more bioactive peptides than standard collagen. With a concentration of 45 % in di- and tripeptides, compared with the usual 10 %. Three natural flavors are available: blackcurrant, vanilla and pear. According to its designers, a single 2 g stick a day is all that's needed for optimum effectiveness.

Natural hair care

Hair Bloom Ceramides is a water-soluble powder dietary supplement formulated with plant extracts enriched with zinc and vitamin B8. This product targets scalp growth, strength and balance thanks to Ceramosides. Laboratoire Pyc reports that Ceramosides phytoceramides demonstrated their efficacy in just three months, with a 12 % increase in hair growth, a 97 % strengthening and a 12 % reduction in excess sebum.

Laboratoire PYC has been committed to this natural approach since 2017. The idea is to give pride of place to the active ingredients and let the rest of the ingredients serve either as a support (plant support), or to provide a pleasant, natural flavor.

Hair Bloom Ceramides includes no superfluous ingredients. Its composition is based on targeted active ingredients and natural carriers such as stevia and natural aromas. Its fruity and floral notes are based on an exclusive Herbal Bliss flavor.

As with all Laboratoire Pyc formulas, these two new products can be customized to meet brand needs.

_{Photo taken from Laboratoire Pyc website.}

Coverpla: worldwide exclusivity on seven Heinz Glas bottles

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6 March 2025

Coverpla designs, manufactures and distributes customizable packaging solutions (bottles, closures and pumps) for brands.

To ensure the longevity of its turnkey offer, and guarantee the quality and security of supply of the bottles it proposes, the Nice-based SME sources from the most renowned glassmakers, such as Pochet, Bormioli Luigi, Verescence and Heinz Glas.

Seven signature models

While Heinz Glas bottles have long been part of the Coverpla catalog, the glassmaker recently decided to give its partner exclusive sales rights for seven of its differently styled bottles (Jens, Juicy, Quadri, Style, Trek, Urban and Yoga). This selection lends itself perfectly to the mix & match of standard products offered by Coverpla.

Coverpla is now the brands' sole contact for these models. Available from stock in two formats (50 and 100 ml), these bottles are ready to play the magic of personalization!

Fedrigoni, EcoVadis Platinum Medal

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5 March 2025

The Fedrigoni Group, one of the world's leading players in specialty papers, self-adhesive materials and RFID solutions, has achieved an EcoVadis score of 90/100 (for the third year running) with a platinum medal for sustainability in 2024.

With a score of 90/100, Fedrigoni has improved by 10 points on the previous year, and maintains its place in the top % ranking of the most virtuous companies.

This is due in particular to the results of its sustainable sourcing program, which has enabled 241 suppliers - through specific training and continuous improvement strategies - to increase their CSR score by an average of 4.5 points. Involving business partners upstream and promoting sustainable practices downstream is proving to be a winning recipe for the Italian group to generate shared value and gain a positive impact on the entire ecosystem.

EcoVadis plays a crucial role in Fedrigoni's trajectory towards achieving the 2030 objectives, by measuring performance in the areas of environment, labor and human rights, ethics and sustainable procurement.

With around 6,000 people in 28 countries and 25,000 products, Fedrigoni sells and distributes in 132 countries thanks in part to recent acquisitions. Sustainability permeates the Group's entire strategy, and it is committed to tracking progress in reducing CO₂ emissions, water consumption, waste management, accelerating sustainability-driven innovation, preventing accidents, promoting an inclusive and learning-friendly environment, and creating value with the communities with which it operates.

"Making Progess" is the company's approach. With transparency, third-party certified results and a long-term vision. By way of example, the Group has replaced single-use plastic with paper solutions, and designed self-adhesive label solutions to improve the recyclability of primary packaging on an industrial scale.

Industries CosmétiquesThe complete watch in cosmetic perfumery

Industries CosmétiquesThe complete watch in cosmetic perfumery

Industries CosmétiquesThe complete watch in cosmetic perfumery

New publication with Cerebiome^® for the intestine-brain-skin axis

Cosmebiome: Innovative clinical study

Significant reduction in perceived stress

Sleep benefits

Benefits for skin appearance

Applications

About Cerebiome - A game-changing psychobiotic

About Lallemand Health Solutions

Traceability and authentication: Selinko joins Japanese group Toppan

A comprehensive offer

Dealing with counterfeiting

A new durable crystalline resin

Skincare: a growing market

To put an end to dandruff

Expanscience supports the Joséphine association

A biomimetic ceramide to preserve the scalp barrier

Laboratoire Pyc to present its nutricosmetics innovations at Cosmoprof Bologna

An orodispersible collagen

Natural hair care

Coverpla: worldwide exclusivity on seven Heinz Glas bottles

Seven signature models

Fedrigoni, EcoVadis Platinum Medal

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Industries CosmétiquesThe complete watch in cosmetic perfumery