To promote healthy aging, researchers have identified various mechanisms and markers capable of limiting the decline of biological functions. Sirtuins are among them. Their influence on longevity depends on the availability of the coenzyme NAD+essential for mitochondrial function and energy production, and AMPK, an energy sensor that guards cellular metabolism.
Thanks to new studies conducted on different models of epidermal and dermal aging, Silab has demonstrated the cross-disciplinary action of its Longevicell® active ingredient. on sirtuins 1, 3, 6 and 7 and their coactivators (NAD+ and AMPK). It thus has a positive effect on numerous mechanisms linked to ageing, notably by improving mitochondrial activity and limiting glycation and the onset of cell senescence.
Rapid anti-aging action for face and body
Thanks to its positive impact on these cellular mechanisms, Longevicell limits protein oxidation and increases cellular energy production in the epidermis, while improving the quality of the dermal matrix.
Silab reports that these effects can be seen as early as 14 days, with remarkable benefits for the face and body: the skin of Caucasian and Asian volunteers is smoother and the complexion brighter. What's more, after 28 days, the skin's elasticity and firmness are enhanced, and wrinkles are reduced. These benefits are perceived by the Caucasian volunteers themselves: 100 % of them consider their skin smoother (body) and more luminous (face), and 95% of them consider this skincare product to be anti-wrinkle.
A traced and secure supply of myrtle
For the development of Longevicell, Silab exploited the oligogalacturonans present in myrtle leaves. Native to the Mediterranean basin, this shrub has been prized for centuries for its ability to enhance beauty. In Antiquity, the Greco-Romans used its essential oil to prepare a floral water with the power to restore freshness and youthfulness to the complexion.
To ensure the sustainability of its supply chain, the company has sourced its raw materials from certified organic Moroccan suppliers. The company has also carried out a control audit on the production stages of the raw material, validating its quality and ensuring its traceability to the harvesting site.
Longevicell is a patented active ingredient recommended for all anti-aging face and body care products at a dose of 1 to 4 %. Available in aqueous solution, it is easy to formulate. It complies with biodiversity regulations and has a content of natural origin greater than or equal to 99.3% (ISO 16128). It complies with international cosmetics regulations (Europe, USA, China, Japan, etc.).
