At the World Congress of Dermatology (WCD) in Singapore, L'Oréal presented its vision for the future of dermatology, unveiling its new research and innovations in the field of skin health.

L'Oréal's Dermatological Beauty division (LDB) has presented the results of two international skin health studies carried out by La Roche-Posay (LRP) and Vichy respectively:

• In the LRP study, the largest of its kind to date involving 48,000 people in 34 countries, half the participants (50 %) reported pigmentation disorders such as vitiligo, post-inflammatory hyperpigmentation or melasma. Nearly a third (28 %) said they had lost quality of life as a result of these disorders, and 44 % said they hid the affected part of their body.
• According to the findings of a survey carried out by Vichy among 20,000 women in 20 countries, 72 % of them feel that hormonal variations have a negative impact on their well-being, and the majority (three out of four women) say that skin problems occur or worsen during menstruation.

During the congress, L'Oréal also highlighted its latest innovations in the fields of skin defense, photoprotection, pigmentation and skin aging, all against a backdrop of sustainable development and inclusion.

New ingredients and Green Sciences

Mexoryl 400 is the patented flagship ingredient of UVMune 400 by La Roche-Posay, the very first L'Oréal technology to protect skin against ultra-long UVA rays and prevent skin damage linked to photoaging, photo pollution and the modification of genes that can lead to skin cancers.

Pro-Xylane by L'Oréal Paris is the first active ingredient derived from Green Sciencesdeveloped from the sugars naturally present in beech bark. Invented over 20 years ago, the Pro-Xylane molecule has since been patented, and has become one of L'Oréal's benchmarks for anti-ageing solutions.

The madecassoside contained in Cicaplast B5 Balm by La Roche-Posay is extracted from the leaves of the Centella Asiaticacombined with water and ethanol derived from sugar cane. This plant extract, known for its antioxidant and anti-inflammatory properties, helps strengthen the skin barrier.

"We are delighted to return to the World Congress of Dermatology armed with new data on skin health that complements the important work of the dermatology community.said Barbara Lavernos, Executive Vice President, Research, Innovation and Technology, L'Oréal. Our extensive research, innovation and growing investment in tech enable us to help solve the most pressing skin and hair problems, from hyperpigmentation and sun protection to acne, dry skin and more, to help more people achieve healthier skin and a better quality of life."

"In partnership with dermatologists around the world, we are advancing skin health for everyone, in their infinite diversity, added Myriam Cohen-Welgryn, General Manager, Dermatological Beauty, L'Oréal Group. By participating in the enrichment of scientific knowledge, creating new sustainable products and augmented services, and supporting people waiting for solutions, we are helping to promote access to skin health for an ever-growing number of people worldwide."

Thanks to its patented enzymatic extraction eco-process, Biolie has developed Saffrever, a saffron flower extract with antioxidant, anti-aging and soothing properties.

An upcycled natural active ingredient...

This aqueous active ingredient is obtained by enzymatic extraction of saffron cultivation by-products. It is derived from upcycled saffron crocus petals.

... with multiple properties

Saffrever inhibits the activity of β-galactosidase and IL-1, making it a highly effective anti-ageing active with soothing properties, according to Biolie. It also has antioxidant properties, repelling up to 90 % of free radicals.

At a time when one in two women is likely to suffer from excessive hair loss at some point in her life¹ The global nutricosmetics market is showing increasing interest in the hair segment. Seppic, with over 10 years' expertise in skin care, is now extending its know-how to hair, with promising clinical results.

The maintenance and renewal of healthy hair is directly correlated with its lipid composition. This is why ceramides, known for their involvement in intracellular lipid formation, play a key role, acting as a barrier to protect the hair cuticle.

With this in mind, Seppic has launched a clinical study on its natural nutraceutical ingredient Ceramosides, obtained from wheat lipids and rich in phytoceramides.

This randomized, placebo-controlled study was carried out on a panel of women of all ages affected by non-pathological hair loss. In just three months, the results highlighted significant effects on various key hair parameters:

• significant hair length growth of 12.5% vs. placebo
• a 2-fold increase in the number of hairs in the growth phase: +11,000 (compared with less than 5,000 in the placebo group)
• a significant 27% reduction in hair loss vs. placebo
• significant improvement in hair's resistance to breakage thanks to increased elasticity
• a significant reduction in scalp sebum in women with oily hair

This new study extends the field of application of Ceramosides, whose anti-aging and moisturizing efficacy on the skin has already been proven in three clinical studies. 

Ceramosides is vegan, guaranteed GMO-free, additive-free, preservative-free and gluten-free. It is certified kosher and also has an organic grade.

_{1 Cleveland Clinic. Hair Loss in Women (online). Accessed in June 2023.}